Propranolol is an FDA-approved beta-blocker to treat hypertension, heart rate dysfunction, and migraine, among other conditions. It is also used off-label to treat anxiety and panic disorder symptoms. It’s essential to be aware of the potential side effects of this — or any — drug. Always seek medical advice from your health care provider before starting a new medication. 

Some Propranolol side effects might include lightheadedness, exhaustion, nausea, loose bowels, constipation, and difficulty sleeping. While many side effects can resolve after a few days or weeks as your body adjusts to the medication, it’s important to contact your doctor if any symptoms worsen or become difficult to manage. Certain medications don’t mix well together, so it is important to do your due diligence before starting Propranolol. 

Read on to learn more about the side effects of Propranolol you need to be aware of.  

Common Side Effects of Propranolol

“The most common side effects are headache, nausea, vomiting, dizziness, and the feeling can cause a sudden drop of blood pressure, low blood sugar, cold hands and feet, and sudden vision problems.”

– Talkspace psychiatrist Dr. Muhammad Munir

Propranolol works for anxiety by blocking the action of chemical messengers like noradrenaline and adrenaline. Yes, it can be effective in relieving symptoms of anxiety, but as with any medication, there are adverse effects like headache and others, including:

Dizziness

Lightheadedness

Drowsiness

Nausea

Stomach pain

Decreased sex drive

Diarrhea and constipation

Hair thinning or loss

Dizziness

Taking Propranolol can cause dizziness, affecting your ability to drive or operate machinery safely.  

Lightheadedness

Lightheadedness is another common side effect of taking Propranolol, possibly leading to fainting spells if not monitored carefully.  

Drowsiness

Propranolol may cause drowsiness. Take notice of when you take Propranolol to determine if it’s affecting your sleep at night.

Nausea

Nausea is a commonly reported side effect of Propranolol. It’s more likely when taken at higher doses. Fortunately, nausea often goes away as your body becomes more used to it being in your system.  

Stomach pain

Stomach pain is another potential side effect of Propranolol. It should be monitored closely since it could indicate an allergic or drug interaction that needs immediate medical attention. Be sure to report any stomach pains to your doctor so they can investigate the cause and determine whether medication changes need to be made.

Decreased sex drive

Decreased libido is a possible consequence of taking Propranolol. However, there isn’t much research yet into why this occurs (and it might be due to general fatigue or caused by other factors). If sexual desire does decrease while using Propranolol, speak with a healthcare professional about potentially switching medications or changing your dosage.

Diarrhea and constipation

Long-term use of Propranolol can cause diarrhea and constipation. Diarrhea tends to be more likely than constipation (although individual experiences will vary). Keep an eye out for either symptom developing over time while using Propranolol — if one becomes concerning, consult your doctor.

Hair thinning or loss

It’s usually temporary (and will reverse once the medication is stopped), but beta-blockers like Propranolol can cause hair loss or thinning. 

Serious Side Effects of Propranolol

One of the most concerning potential side effects of Propranolol is hallucinations. If you start to hallucinate while on Propranolol, medical intervention is essential.  

Though rare, Propranolol has been linked to depression and mood changes in some research. It’s also been found to cause memory problems in some people. 

Hallucinations 

Vomiting

Memory loss

Muscle weakness

Muscle cramps

Blood sugar changes

Shakiness

Fluid retention 

Insomnia and nightmares 

Allergic reaction

Cold hands or feet

Weight gain from Propranolol

Some side effects are more serious and might indicate a life-threatening allergic reaction. Seek medical attention immediately if you experience:

Swelling of the face or hands

Difficulty breathing, including wheezing

Skin rash

Do Propranolol Side Effects Go Away?

Most people find that their body adjusts to Propranolol over time and they no longer have side effects. Nevertheless, you might want to consult your doctor if symptoms persist or worsen over time. They can discuss changing your dose or switching to an alternate drug.

How long do Propranolol side effects last?

Most people feel some improvement anywhere from a few days to a few weeks after starting Propranolol. This is different for everyone though, and side effects can significantly resolve or worsen over time, especially if your doctor changes your dosage.  

Long-Term Side Effects of Propranolol

Long-term side effects of Propranolol are possible. Not everyone will experience them, but being aware of them is important. Weight gain is one potential long-term effect. Prolonged use also might cause certain side effects to worsen. 

High doses of Propranolol used for a long time might increase the severity of heart problems. It also can mask some symptoms of low blood sugar in people with diabetes, which can be dangerous.

If you do want to stop taking Propranolol after an extended period of time, be sure to work with a doctor to do so to avoid Propranolol withdrawal.

How to Manage Propranolol Side Effects

The best way to manage Propranolol side effects is by closely following your doctor’s dosing directions. Monitor any reactions or side effects and let your doctor know if you’re experiencing any worsening symptoms.  

Fortunately, there are some easy ways to minimize the risk of Propranolol side effects. 

Live a healthy lifestyle

Focus on nutrition

Get exercise

Make rest a priority 

Limit or avoid alcohol and caffeine consumption 

Use self-care calming activities like yoga or meditation

Incorporating relaxation techniques into a daily routine helps relieve stress and can mitigate the risk of taking Propranolol. It allows you to focus more energy on maintaining a positive mindset instead of worrying about potential negative consequences associated with this drug.

See if Propranolol Is Right for You 

Propranolol side effects can range from mild to severe depending on many factors. It’s crucial to know what you might experience from taking this drug. While many side effects will go away over time or with dose adjustment, others can require more intensive management. Before you begin Propranolol, your doctor will review the risks and benefits. 

With the help of Talkspace Psychiatry, you can find out if Propranolol is suitable for you in an online setting that offers convenience and privacy. Take the first step in understanding how to manage Propranolol’s side effects by signing up with Talkspace. Our mental healthcare experts are trained and experienced and can help you find treatment solutions tailored to your individual needs. Should a psychiatrist find it best for your treatment plan, you can get a prescription for Propranolol online. Get started at Talkspace today.